Season 2

The second season mainly focuses on the senior year and the relationship between Blair and Chuck.

The first half of the season shows Serena's growing fame as a trend-setter which draws the attention of Blair as their friendship is tested when Poppy Lifton arrives. Nate faces the aftermath of his father's criminal past and pursues a relationship with Vanessa, who becomes tangled into the world of the Upper East Side. Jenny reignites her rebellious nature by pursuing her career as a fashion designer, thus challenging Rufus' skills as a parent.  Dan's friendship with Nate and his relationship with Serena slowly converts him from a social outcast to an insider. The show finished its first half during the first week of December, with the shocking death of Bart Bass.

The second half of the season reveals the impact of Bart's death, causing a major change for Chuck that consequently leads to the growth of Rufus and Lily's relationship, the exposure of the two having a son together contributed to the weakening of Dan and Serena's relationship.

As the storylines proceeded, the role of "Gossip Girl" is slightly reduced. She continues to run her blog, but she keeps the critical information for herself, sending it in the final episode as the last blast, where Serena decides to find out who "Gossip Girl" really is, but in the end fails. The season finale ended with a well-received kiss between Blair and Chuck…